If you make a clone of a clone of a clone ... (58 times) ... of a mouse, it becomes mutated. 
<br /><a href='https://www.reuters.com/business/healthcare-pharmaceuticals/mouse-study-shows-repeated-cloning-causes-grave-genetic-mutations-2026-03-24/'>https://www.reuters.com/business/healthcare-pharmaceuticals/mouse-study-shows-repeated-cloning-causes-grave-genetic-mutations-2026-03-24/</a>